Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14587666 | 0.90 | ALDH1A1 (0.57) | NTRK1ALDH1A1HPGDRAB9APPARG | |
| SCHEMBL14587693 | 0.86 | RAB9A (0.46) | NTRK1ALDH1A1HPGDRAB9APPARG | |
| SCHEMBL14587681 | 0.86 | NTRK1 (0.51) | NTRK1ALDH1A1RAB9APPARGNPC1 | |
| SCHEMBL5010405 | 0.85 | PPARG (0.59) | NTRK1ALDH1A1RAB9APPARGNPC1 | |
| SCHEMBL14587772 | 0.85 | ALDH1A1 (0.43) | NTRK1ALDH1A1RAB9APPARGNPC1 | |
| SCHEMBL14587703 | 0.85 | MEN1 (0.47) | NTRK1ALDH1A1PPARG | |
| SCHEMBL14587705 | 0.85 | MEN1 (0.47) | NTRK1ALDH1A1PPARG | |
| SCHEMBL5010568 | 0.85 | NPC1 (0.46) | ALDH1A1RAB9APPARGNPC1CYP1A2 | |
| SCHEMBL5008267 | 0.85 | PPARG (0.45) | NTRK1ALDH1A1HPGDRAB9APPARG | |
| SCHEMBL14587696 | 0.84 | ADORA2A (0.43) | NTRK1ALDH1A1RAB9APPARGNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | NTRK1 4549/4885ALDH1A1 1278/4885HPGD 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.