Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14587735 | 0.88 | NTRK1 (0.54) | RAB9ANPC1PPARGNTRK1WDR5 | |
| SCHEMBL14587772 | 0.88 | ALDH1A1 (0.43) | RAB9ANPC1PPARGNTRK1ALDH1A1 | |
| SCHEMBL14587694 | 0.86 | RAB9A (0.56) | RAB9ANPC1HPGDPPARGNTRK1 | |
| SCHEMBL14587722 | 0.86 | NTRK1 (0.54) | RAB9ANPC1HPGDPPARGNTRK1 | |
| SCHEMBL14587681 | 0.84 | NTRK1 (0.51) | RAB9ANPC1PPARGNTRK1ALDH1A1 | |
| SCHEMBL5013431 | 0.84 | NPC1 (0.49) | RAB9ANPC1PPARG | |
| SCHEMBL14301497 | 0.84 | PPARG (0.44) | RAB9ANPC1PPARGNTRK1ALDH1A1 | |
| SCHEMBL14587786 | 0.83 | NPC1 (0.44) | RAB9ANPC1PPARGNTRK1WDR5 | |
| SCHEMBL5010362 | 0.83 | PPARG (0.50) | RAB9ANPC1HPGDPPARGALDH1A1 | |
| SCHEMBL14587641 | 0.83 | PPARG (0.41) | PPARGNTRK1ALDH1A1HTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | RAB9A 2748/4885NPC1 2838/4885HPGD 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.