Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160283 | 0.84 | MEN1 (0.38) | DHFRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL91392 | 0.75 | — | — | |
| SCHEMBL31693622 | 0.72 | CA12 (0.40) | ALDH1A1KMT2ATLR8MEN1HTT | |
| SCHEMBL6755475 | 0.71 | DHFR (0.45) | DHFRALDH1A1TLR7KMT2ATLR8 | |
| SCHEMBL19901535 | 0.70 | HRH3 (0.32) | TLR7TLR8 | |
| SCHEMBL17514350 | 0.68 | MLYCD (0.40) | DHFRALDH1A1TLR7KMT2ATLR8 | |
| SCHEMBL16516215 | 0.67 | MLYCD (0.39) | DHFRALDH1A1TLR7KMT2AMEN1 | |
| SCHEMBL6753235 | 0.67 | TLR7 (0.46) | DHFRALDH1A1TLR7KMT2ATLR8 | |
| SCHEMBL1025561 | 0.65 | DHFR (0.47) | DHFRALDH1A1TLR7KMT2ATLR8 | |
| SCHEMBL2364943 | 0.65 | DHFR (0.47) | DHFRALDH1A1TLR7KMT2ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316734-B1 | FURAZANYL UREAS | BAYER AG (DE) | 1991-07-03 | — | — | EP | claimed |
| EP-0316734-A2 | Furazanyl ureas | BAYER AG (DE) | 1989-05-24 | — | — | EP | claimed |
| EP-4066834-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF PI3K-GAMMA MEDIATED DISORDERS | Infinity Pharmaceuticals, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |
| US-10785979-B2 | Substituted ketoxime benzoylamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-09-29 | — | — | US | disclosed |
| EP-3341363-B1 | SUBSTITUTED KETOXIME BENZOYLAMIDE | BAYER CROPSCIENCE AG (DE) | 2019-07-24 | — | — | EP | disclosed |
| US-20180235224-A1 | SUBSTITUTED KETOXIME BENZOYLAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-08-23 | — | — | US | disclosed |
| EP-3341363-A1 | SUBSTITUTED KETOXIME BENZOYLAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017032728-A1 | SUBSTITUTED KETOXIME BENZOYLAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-02 | — | — | WO | disclosed |
| EP-2817297-B1 | HERBICIDALLY ACTIVE 3-(SULFINYLAMINO)-BENZAMIDES | BAYER IP GMBH (DE) | 2016-02-17 | — | — | EP | disclosed |
| US-9198425-B2 | Herbicidally-effective sulfinyl aminobenzamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-9167819-B2 | Herbicidal 3-(sulfin-/sulfonimidoyl)-benzamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-8288316-B2 | N-(1,2,5-oxadiazol-3-yl)benzamides and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2012-10-16 | — | — | US | disclosed |
| WO-2012123416-A1 | N-(1,2,5-OXADIAZOL-3-YL)PYRIDINECARBOXAMIDES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-09-20 | — | — | WO | disclosed |
| WO-2012123409-A1 | N-(1,2,5-OXADIAZOL-3-YL)-, N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)BICYCLOARYLCARBOXAMIDES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-09-20 | — | — | WO | disclosed |
| EP-2480539-A1 | N-(1,2,5-OXADIAZOL-3-YL) BENZAMIDES AND THE USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2012-08-01 | — | — | EP | disclosed |
| US-20110152084-A1 | N-(1,2,5-OXADIAZOL-3-YL)BENZAMIDES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| WO-2011035874-A1 | N-(1,2,5-OXADIAZOL-3-YL) BENZAMIDES AND THE USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-03-31 | — | — | WO | disclosed |
| EP-0316734-B1 | FURAZANYL UREAS | BAYER AG (DE) | 1991-07-03 | — | — | EP | disclosed |
| US-4886823-A | Furazanylurea acaricides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| EP-0316734-A2 | Furazanyl ureas | BAYER AG (DE) | 1989-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10785979-B2 | Substituted ketoxime benzoylamides | KYAT3, KMO, OXA1L | DHFR 370/4885ALDH1A1 591/4885TLR7 3754/4885 |
| US-20180235224-A1 | SUBSTITUTED KETOXIME BENZOYLAMIDES | KYAT3, KMO, OXA1L | DHFR 370/4885ALDH1A1 591/4885TLR7 3754/4885 |
| US-20110152084-A1 | N-(1,2,5-OXADIAZOL-3-YL)BENZAMIDES AND THEIR USE AS HERBICIDES | AOX1, CBR3, ZYX | DHFR 534/4885ALDH1A1 109/4885TLR7 4531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.