Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14687530 | 0.83 | TDP1 (0.41) | CYP3A4TDP1PRNPMEN1KMT2A | |
| SCHEMBL3425344 | 0.80 | CYP3A4 (0.38) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL3940105 | 0.80 | ALDH1A1 (0.46) | CYP3A4TDP1MEN1KMT2APARP1 | |
| SCHEMBL14627617 | 0.77 | PRNP (0.33) | PRNPMEN1KMT2A | |
| SCHEMBL5425957 | 0.76 | LOXL2 (0.35) | CYP3A4TDP1DRD1PNMT | |
| SCHEMBL14596133 | 0.76 | CA1 (0.38) | CYP3A4TDP1MEN1KMT2ADRD1 | |
| SCHEMBL5107 | 0.75 | ALDH1A1 (0.44) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL146878 | 0.75 | ALDH1A1 (0.44) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL7491891 | 0.75 | CYP3A4 (0.50) | CYP3A4TDP1PRNPMEN1KMT2A | |
| SCHEMBL29496111 | 0.75 | ALDH1A1 (0.44) | CYP3A4TDP1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | MPI, ITPA, DCPS | CYP3A4 1000/4885TDP1 655/4885PRNP 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.