Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19009976 | 0.83 | CYP3A4 (0.37) | LOXL2CYP3A4TDP1DPP4PNMT | |
| Bromide SCHEMBL15463465 | 0.82 | CYP3A4 (0.35) | LOXL2CYP3A4TDP1DPP4CYP2A6 | |
| Bromide SCHEMBL14687033 | 0.81 | CYP3A4 (0.34) | LOXL2CYP3A4TDP1DPP4CYP2A6 | |
| SCHEMBL14627616 | 0.80 | KDM4E (0.31) | LOXL2 | |
| SCHEMBL3940105 | 0.78 | ALDH1A1 (0.46) | CYP3A4TDP1DRD1 | |
| SCHEMBL14596146 | 0.76 | CYP3A4 (0.39) | CYP3A4TDP1PNMTDRD1 | |
| SCHEMBL12700939 | 0.75 | CYP3A4 (0.46) | LOXL2CYP3A4TDP1DPP4PNMT | |
| SCHEMBL3425344 | 0.75 | CYP3A4 (0.38) | CYP3A4TDP1DRD1 | |
| SCHEMBL6700842 | 0.72 | ASIC3 (0.42) | LOXL2CYP3A4TDP1CYP2A6 | |
| SCHEMBL29463705 | 0.72 | PNMT (0.52) | LOXL2CYP3A4TDP1DPP4PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-01-11 | — | — | US | disclosed |
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | MPI, ITPA, DCPS | LOXL2 3249/4885CYP3A4 1000/4885TDP1 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.