SCHEMBL14596358

SCHEMBL14596358

O=C(Cc1ccccc1)ON=Cc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 2/20 0.57
L3MBTL1 Q9Y468 4/20 0.49
MAPK1 P28482 2/20 0.49
ALDH1A1 P00352 2/20 0.49
MIF P14174 4/20 0.47
PAM P19021 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
HTT P42858 1/20 0.47
TSHR P16473 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
FAAH O00519 2/20 0.45
THRB P10828 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
AKR1B1 P15121 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11963972 1.00 PLA2G7 (0.57) PLA2G7L3MBTL1MAPK1ALDH1A1MIF
SCHEMBL11963978 0.84 ALDH1A1 (0.47) PLA2G7L3MBTL1ALDH1A1SMN1; SMN2TDP1
SCHEMBL14596361 0.84 ALDH1A1 (0.47) PLA2G7L3MBTL1ALDH1A1SMN1; SMN2TDP1
SCHEMBL5764787 0.82 PLA2G7 (0.47) PLA2G7MAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL28216697 0.81 PLA2G7 (0.59) PLA2G7MIFFAAHNPC1RAB9A
SCHEMBL11963957 0.81 PLA2G7 (0.59) PLA2G7MIFFAAHNPC1RAB9A
SCHEMBL29208564 0.78 MIF (0.61) PLA2G7MIFFAAHNPC1RAB9A
SCHEMBL11963956 0.78 MIF (0.61) PLA2G7MIFFAAHNPC1RAB9A
SCHEMBL6420965 0.77 PLA2G7 (0.69) PLA2G7L3MBTL1ALDH1A1MIFFAAH
SCHEMBL10332554 0.76 PLA2G7 (0.67) PLA2G7L3MBTL1ALDH1A1MIFFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007034616-A1 TWO-PHOTON-ABSORBING RECORDING MEDIUM, TWO-PHOTON-ABSORBING RECORDING/REPRODUCING METHOD, AND TWO-PHOTON-ABSORBING RECORDING/REPRODUCING APPARATUS FUJIFILM CORPORATION (JP) 2007-03-29 WO disclosed