Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14596358 | 0.82 | PLA2G7 (0.57) | PLA2G7ALDH1A1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL11963972 | 0.82 | PLA2G7 (0.57) | PLA2G7ALDH1A1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL28043254 | 0.76 | NPC1 (0.56) | KMT2AALDH1A1MEN1SMN1; SMN2KDM4E | |
| SCHEMBL7638188 | 0.73 | ALDH1A1 (0.67) | KMT2AALDH1A1MEN1ALOX15MAPK1 | |
| SCHEMBL11963957 | 0.71 | PLA2G7 (0.59) | PLA2G7KMT2AMEN1 | |
| SCHEMBL28216697 | 0.71 | PLA2G7 (0.59) | PLA2G7KMT2AMEN1 | |
| SCHEMBL14596361 | 0.71 | ALDH1A1 (0.47) | PLA2G7KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL11963978 | 0.71 | ALDH1A1 (0.47) | PLA2G7KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL10824094 | 0.70 | KMO (0.46) | KMT2AALDH1A1MEN1SMN1; SMN2KDM4E | |
| SCHEMBL7530478 | 0.70 | HAO1 (0.51) | KMT2AALDH1A1MEN1KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650189-A1 | BENZYLAMINE DERIVATIVE | Zeria Pharmaceutical Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |