SCHEMBL14596361

SCHEMBL14596361

O=C(Cc1ccccc1)ON=Cc1ccc2ccccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
KDM4E B2RXH2 5/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
LMNA P02545 5/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HPGD P15428 2/20 0.46
GRIN2D O15399 2/20 0.46
GRIN3B O60391 2/20 0.46
GRIN1 Q05586 2/20 0.46
GRIN2A Q12879 2/20 0.46
GRIN2B Q13224 2/20 0.46
GRIN2C Q14957 2/20 0.46
GRIN3A Q8TCU5 2/20 0.46
RAB9A P51151 1/20 0.45
PLA2G7 Q13093 1/20 0.43
POLB P06746 1/20 0.43
PPARG P37231 1/20 0.43
NCOA2 Q15596 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11963978 1.00 ALDH1A1 (0.47) ALDH1A1KDM4EL3MBTL1LMNAMEN1
SCHEMBL11963972 0.84 PLA2G7 (0.57) ALDH1A1L3MBTL1SMN1; SMN2RAB9APLA2G7
SCHEMBL14596358 0.84 PLA2G7 (0.57) ALDH1A1L3MBTL1SMN1; SMN2RAB9APLA2G7
SCHEMBL27178032 0.75 KMT2A (0.64) ALDH1A1KDM4EL3MBTL1LMNAMEN1
SCHEMBL27178047 0.75 KMT2A (0.64) ALDH1A1KDM4EL3MBTL1LMNAMEN1
SCHEMBL6208719 0.75 PPARG (0.51) ALDH1A1KDM4EL3MBTL1LMNAMEN1
SCHEMBL6208715 0.75 PPARG (0.51) ALDH1A1KDM4EL3MBTL1LMNAMEN1
SCHEMBL11963967 0.71 L3MBTL1 (0.55) ALDH1A1KDM4EL3MBTL1LMNAMEN1
SCHEMBL31667880 0.71 L3MBTL1 (0.55) ALDH1A1KDM4EL3MBTL1LMNAMEN1
SCHEMBL5764787 0.71 PLA2G7 (0.47) ALDH1A1KDM4ELMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007034616-A1 TWO-PHOTON-ABSORBING RECORDING MEDIUM, TWO-PHOTON-ABSORBING RECORDING/REPRODUCING METHOD, AND TWO-PHOTON-ABSORBING RECORDING/REPRODUCING APPARATUS FUJIFILM CORPORATION (JP) 2007-03-29 WO disclosed