Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 3/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | PRF1 | P14222 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152697 | 0.87 | CYP2A6 (0.58) | CYP2A6ALDH1A1MAPTKDM4EERN1 | |
| SCHEMBL14341668 | 0.83 | PRF1 (0.44) | ALDH1A1MAPTKDM4EPRF1CYP1A2 | |
| SCHEMBL34459993 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4ECYP1A2CYP2C19 | |
| SCHEMBL28633959 | 0.75 | ESR1 (0.49) | ALDH1A1MAPTCYP1A2CYP2C19ESR1 | |
| SCHEMBL5544081 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4ECYP1A2CYP2C19 | |
| SCHEMBL4797361 | 0.75 | ALDH1A1 (0.44) | CYP2A6ALDH1A1MAPTKDM4EPRF1 | |
| SCHEMBL6811552 | 0.74 | CYP2A6 (0.74) | CYP2A6ALDH1A1ERN1PRF1 | |
| SCHEMBL1121724 | 0.74 | CYP2A6 (0.56) | CYP2A6ALDH1A1MAPTKDM4EERN1 | |
| SCHEMBL14599487 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EPRF1CYP1A2 | |
| SCHEMBL30197394 | 0.74 | CYP2A6 (0.74) | CYP2A6ALDH1A1ERN1PRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101133056-B | Antitumor compounds | NAT HEALTH RESEARCH INSTITUTES | 2010-12-01 | — | — | CN | disclosed |
| US-7456289-B2 | Anti-tumor compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-11-25 | — | — | US | disclosed |
| CN-101133056-A | Antitumor compounds | NAT HEALTH RESEARCH INSTITUTES (CN) | 2008-02-27 | — | — | CN | disclosed |
| EP-1838711-A2 | ANTI-TUMOR COMPOUNDS | National Health Research Institutes (TW) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006074041-A2 | ANTI-TUMOR COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2006-07-13 | — | — | WO | disclosed |
| US-20060148801-A1 | Anti-tumor compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148801-A1 | Anti-tumor compounds | TUBB1, TUBB3, TUBB | CYP2A6 4731/4885ALDH1A1 2627/4885MAPT 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.