Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14609887 | 0.86 | ATM (0.42) | ALDH1A1MEN1KMT2AMKNK1MKNK2 | |
| SCHEMBL5211765 | 0.85 | ALDH1A1 (0.42) | KDM4EALDH1A1KMT2A | |
| SCHEMBL5207866 | 0.84 | GABRA1 (0.35) | KDM4EALDH1A1KMT2A | |
| SCHEMBL5213384 | 0.84 | RXRA (0.47) | KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL5211701 | 0.83 | MKNK1 (0.42) | ALDH1A1MEN1KMT2AMKNK1MKNK2 | |
| SCHEMBL5212748 | 0.81 | LMNA (0.51) | KMT2A | |
| SCHEMBL5211934 | 0.81 | MAPT (0.43) | TSPOMEN1KMT2A | |
| SCHEMBL5215187 | 0.80 | FAAH (0.42) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5212489 | 0.80 | RXRA (0.43) | KMT2A | |
| SCHEMBL5215764 | 0.80 | NPC1 (0.48) | KDM4EALDH1A1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |