Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | CPA3 | P15088 | 2/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14558129 | 0.88 | CYP1A2 (0.40) | FOLH1CYP1A2CPA1CPA3CPB1 | |
| SCHEMBL14611119 | 0.83 | CYP1A2 (0.51) | FOLH1CYP1A2 | |
| SCHEMBL252900 | 0.79 | CYP1A2 (0.68) | FOLH1CYP1A2CPA1CPA3CPB1 | |
| SCHEMBL9007628 | 0.79 | CYP1A2 (0.68) | FOLH1CYP1A2CPA1CPA3CPB1 | |
| SCHEMBL629350 | 0.79 | CYP1A2 (0.68) | FOLH1CYP1A2CPA1CPA3CPB1 | |
| SCHEMBL5096045 | 0.79 | PTGS2 (0.51) | FOLH1CYP1A2CPA1CPA3CPB1 | |
| SCHEMBL14610928 | 0.77 | HPGD (0.50) | — | |
| SCHEMBL11078876 | 0.76 | ALDH1A1 (0.42) | FOLH1 | |
| SCHEMBL9007635 | 0.73 | CYP1A2 (0.49) | FOLH1CYP1A2CPA1CPA3CPB1 | |
| SCHEMBL6005075 | 0.71 | KMO (0.48) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179819-B2 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |