SCHEMBL1461246

SCHEMBL1461246

CC(CO)C1CCC(CO)CC1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
ESR2 Q92731 1/20 0.32
APLNR P35414 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140296 0.87
SCHEMBL8056802 0.87
SCHEMBL16712669 0.87
SCHEMBL4917793 0.84 SHBG (0.37) ESR1CYP3A4CYP2C9ESR2APLNR
SCHEMBL19721696 0.81 TSHR (0.37) TSHR
SCHEMBL12880509 0.80 MAPT (0.34) CYP2C9TSHR
SCHEMBL8960427 0.80 TSHR (0.34) TSHR
SCHEMBL9815797 0.80 APLNR (0.35) ESR1CYP3A4CYP2C9ESR2APLNR
SCHEMBL760536 0.80 APLNR (0.35) ESR1CYP3A4CYP2C9ESR2APLNR
SCHEMBL158458 0.80 APLNR (0.35) ESR1CYP3A4CYP2C9ESR2APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2470008-A2 USE OF CYCLOALIPHATIC DIOLS AS BIOCIDES BASF SE (DE) 2012-07-04 EP claimed
US-20120157548-A1 USE OF CYCLOALIPHATIC DIOLS AS BIOCIDES BASF SE (DE) 2012-06-21 US claimed
WO-2011023540-A2 USE OF CYCLOALIPHATIC DIOLS AS BIOCIDES BASF SE (DE) 2011-03-03 WO claimed
WO-2023117119-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-06-29 WO disclosed
CN-115968259-A Robust flavor emulsions 国际香精香料公司 2023-04-14 CN disclosed
CN-108690195-B Composition for flexible substrate and flexible substrate 奇美实业股份有限公司 2022-07-05 CN disclosed
EP-3787904-A1 SYSTEM AND METHOD FOR PRINTING AND DRYING FLAVORS AND FRAGRANCES International Flavors & Fragrances Inc. (US) 2021-03-10 EP disclosed
CN-108690195-A Composition for flexible substrate and flexible substrate 奇美实业股份有限公司 2018-10-23 CN disclosed
EP-2279219-B1 USE OF A CYCLOHEXANE DIOL MIXTURE FOR MANUFACTURING POLYMERS BASF SE (DE) 2013-04-17 EP disclosed
US-8329795-B2 Oil based polyols or diacids esterified with oxo-acids or oxo-alcohols for producing plasticizers EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-12-11 US disclosed
EP-2470008-A2 USE OF CYCLOALIPHATIC DIOLS AS BIOCIDES BASF SE (DE) 2012-07-04 EP disclosed
US-20120157548-A1 USE OF CYCLOALIPHATIC DIOLS AS BIOCIDES BASF SE (DE) 2012-06-21 US disclosed
WO-2011023540-A2 USE OF CYCLOALIPHATIC DIOLS AS BIOCIDES BASF SE (DE) 2011-03-03 WO disclosed
US-20110040030-A1 USE OF A CYCLOHEXANE DIOL MIXTURE FOR MANUFACTURING POLYMERS BASF SE (DE) 2011-02-17 US disclosed
US-20110040030-A1 USE OF A CYCLOHEXANE DIOL MIXTURE FOR MANUFACTURING POLYMERS BASF SE (DE) 2011-02-17 US disclosed
US-20110009548-A1 OIL BASED POLYOLS OR DIACIDS ESTERIFIED WITH OXO-ACIDS OR OXO-ALCOHOLS FOR PRODUCING PLASTICIZERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-01-13 US disclosed
WO-2011005822-A1 OIL BASED POLYOLS OR DIACIDS ESTERIFIED WITH OXO-ACIDS OR OXO-ALCOHOLS FOR PRODUCING PLASTICIZERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-01-13 WO disclosed
WO-2009138387-A1 USE OF A CYCLOHEXANE DIOL MIXTURE FOR MANUFACTURING POLYMERS BASF SE (DE) 2009-11-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009548-A1 OIL BASED POLYOLS OR DIACIDS ESTERIFIED WITH OXO-ACIDS OR OXO-ALCOHOLS FOR PRODUCING PLASTICIZERS DGAT2, DGAT1, FASN ESR1 1626/4885CYP3A4 940/4885CYP2C9 910/4885
US-20120157548-A1 USE OF CYCLOALIPHATIC DIOLS AS BIOCIDES DDT, DBH, GABBR1 ESR1 3905/4885CYP3A4 1946/4885CYP2C9 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.