Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 7/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14613091 | 0.95 | TDP1 (0.52) | TDP1NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL14613142 | 0.87 | TSHR (0.46) | TDP1NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL13291855 | 0.84 | TDP1 (0.56) | TDP1NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL28907665 | 0.83 | ALDH1A1 (0.69) | NPC1MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL21014718 | 0.83 | NPC1 (0.55) | TDP1NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL1410185 | 0.82 | TDP1 (0.81) | TDP1NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL23496578 | 0.81 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL3386629 | 0.81 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL16422182 | 0.81 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL15962622 | 0.81 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043234-A1 | Use of functionalized onium salts as a soluble support for organic synthesis | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043234-A1 | Use of functionalized onium salts as a soluble support for organic synthesis | NOS1, NOS2, F12 | TDP1 2488/4885NPC1 1370/4885MAPT 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.