Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14613091 | 0.89 | TDP1 (0.52) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL14613138 | 0.87 | TDP1 (0.55) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11854031 | 0.82 | TDP1 (0.52) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL24305508 | 0.81 | ESR1 (0.46) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL29083864 | 0.81 | ESR1 (0.46) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10488203 | 0.81 | ALDH1A1 (0.70) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL11852642 | 0.81 | LMNA (0.64) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL28142738 | 0.81 | KMT2A (0.49) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL14369815 | 0.81 | TDP1 (0.53) | TSHRLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL1449565 | 0.80 | TDP1 (0.70) | TSHRLMNATDP1ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043234-A1 | Use of functionalized onium salts as a soluble support for organic synthesis | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043234-A1 | Use of functionalized onium salts as a soluble support for organic synthesis | NOS1, NOS2, F12 | TSHR 3095/4885LMNA 1916/4885CYP1A2 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.