Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29582154 | 0.78 | PI4KA (0.36) | — | |
| SCHEMBL14584045 | 0.77 | SRC (0.33) | ABL1BCR | |
| SCHEMBL12299464 | 0.74 | L3MBTL1 (0.43) | — | |
| SCHEMBL10266747 | 0.67 | PIK3CD (0.35) | XDHABL1 | |
| SCHEMBL14627435 | 0.65 | SSTR4 (0.50) | — | |
| SCHEMBL2244617 | 0.63 | XDH (0.46) | XDHABL1BCR | |
| SCHEMBL21137627 | 0.63 | SLC9A1 (0.43) | XDH | |
| SCHEMBL10050009 | 0.62 | DGAT1 (0.33) | — | |
| SCHEMBL21719169 | 0.61 | DGAT1 (0.34) | — | |
| SCHEMBL11922157 | 0.61 | NTRK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043057-A1 | Lonidamine analogs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-02-22 | — | — | US | disclosed |
| US-20070015771-A1 | Lonidamine analogs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015771-A1 | Lonidamine analogs | LONP1, LPXN, QDPR | XDH 2132/4885ABL1 4876/4885BCR 3914/4885 |
| US-20070043057-A1 | Lonidamine analogs | LONP1, LPXN, QDPR | XDH 2132/4885ABL1 4876/4885BCR 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.