Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645917 | 0.82 | MEN1 (0.65) | TRPV3MEN1RAB9AKMT2AASIC3 | |
| SCHEMBL523614 | 0.80 | NPSR1 (0.54) | KDM4ECYP3A4MAPTPRMT6 | |
| SCHEMBL12061321 | 0.79 | HDAC1 (0.56) | TRPV3MEN1RAB9AKMT2AASIC3 | |
| SCHEMBL15217629 | 0.79 | KDM4E (0.57) | RAB9APDE10ATDP1KDM4E | |
| SCHEMBL13283433 | 0.79 | RAB9A (0.60) | TRPV3MEN1RAB9AKMT2AASIC3 | |
| SCHEMBL19297802 | 0.78 | PRMT6 (0.51) | TRPV3PRMT6 | |
| SCHEMBL5114437 | 0.78 | MEN1 (0.65) | TRPV3MEN1RAB9AKMT2AASIC3 | |
| SCHEMBL13830900 | 0.77 | RAB9A (0.58) | TRPV3MEN1RAB9AKMT2AASIC3 | |
| SCHEMBL13831063 | 0.76 | MEN1 (0.52) | TRPV3MEN1RAB9AKMT2AASIC3 | |
| SCHEMBL19143346 | 0.76 | ASIC3 (0.44) | TRPV3ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |