Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333040 | 0.91 | CXCR4 (0.52) | NPSR1CXCR4KDM4ECYP3A4MAPT | |
| SCHEMBL8986161 | 0.89 | NPSR1 (0.46) | NPSR1CXCR4KDM4ECYP3A4MAPT | |
| SCHEMBL14076725 | 0.89 | NPSR1 (0.50) | NPSR1CXCR4KDM4ECYP3A4MAPT | |
| SCHEMBL2476858 | 0.86 | SMN1; SMN2 (0.53) | NPSR1CXCR4CYP3A4SMN1; SMN2 | |
| SCHEMBL29791992 | 0.86 | SMN1; SMN2 (0.53) | NPSR1CXCR4CYP3A4SMN1; SMN2 | |
| SCHEMBL31330291 | 0.84 | KDM1A (0.47) | NPSR1CXCR4KDM4ECYP3A4MAPT | |
| SCHEMBL2679367 | 0.84 | KDM1A (0.47) | NPSR1CXCR4KDM4ECYP3A4MAPT | |
| SCHEMBL7788876 | 0.84 | NOS3 (0.45) | NPSR1CXCR4 | |
| SCHEMBL12536038 | 0.84 | NPSR1 (0.41) | NPSR1CXCR4KDM4ECYP3A4MAPT | |
| SCHEMBL13464907 | 0.84 | NPSR1 (0.41) | NPSR1CXCR4KDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11730726-B2 | Dimeric immuno-modulatory compounds against cereblon-based mechanisms | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-11351260-B2 | Photocleavable cobalt-nitrosyl complex and nitric oxide carrier containing the same | DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-06-07 | — | — | US | disclosed |
| US-20210052730-A1 | Photocleavable Cobalt-Nitrosyl Complex and Nitric Oxide Carrier Containing the Same | DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2021-02-25 | — | — | US | disclosed |
| EP-2415742-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | Sumitomo Chemical Company, Limited (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120029195-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-0934924-B1 | NOVEL DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6576642-B2 | Inhibitors of the production of Ig E antibodies, antiallergens | KOWA CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| US-20010039279-A1 | Diamide compounds and compositions containing the same | KOWA CO., LTD. (JP) | 2001-11-08 | — | — | US | disclosed |
| US-6297283-B1 | EXCELLENT INHIBITORY EFFECT ON THE PRODUCTION OF AN IGE ANTIBODY AND ARE HENCE USEFUL AS ANTIALLERGIC AGENTS | KOWA CO., LTD. (JP) | 2001-10-02 | — | — | US | disclosed |
| EP-0934924-A1 | NOVEL DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039279-A1 | Diamide compounds and compositions containing the same | HRH4, HRH2, HRH1 | NPSR1 2752/4885CXCR4 836/4885KDM4E 721/4885 |
| US-11730726-B2 | Dimeric immuno-modulatory compounds against cereblon-based mechanisms | CRBN, CD4, CD74 | NPSR1 4092/4885CXCR4 481/4885KDM4E 3212/4885 |
| US-20210052730-A1 | Photocleavable Cobalt-Nitrosyl Complex and Nitric Oxide Carrier Containing the Same | NOS2, NOS1, PPOX | NPSR1 2128/4885CXCR4 2379/4885KDM4E 1945/4885 |
| US-11351260-B2 | Photocleavable cobalt-nitrosyl complex and nitric oxide carrier containing the same | NOS2, NOS1, PPOX | NPSR1 2128/4885CXCR4 2379/4885KDM4E 1945/4885 |
| US-20120029195-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | ADH1A, ADH1C, ADH5 | NPSR1 3205/4885CXCR4 1117/4885KDM4E 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.