Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | MGLL | Q99685 | 2/20 | 0.62 |
| ▸ | BCHE | P06276 | 4/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12040562 | 0.91 | LTA4H (0.77) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL12630258 | 0.91 | LTA4H (0.77) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL128703 | 0.88 | LMNA (0.67) | BCHEL3MBTL1LMNACYP1A2PTGS1 | |
| SCHEMBL6284506 | 0.87 | LTA4H (0.66) | LTA4HEPHX2MGLLBCHESIGMAR1 | |
| SCHEMBL11051776 | 0.87 | LTA4H (0.66) | LTA4HEPHX2MGLLBCHESIGMAR1 | |
| SCHEMBL13979617 | 0.86 | DRD2 (0.62) | FFAR1TDP1L3MBTL1DRD2DRD4 | |
| SCHEMBL6283332 | 0.85 | LTA4H (0.68) | LTA4HEPHX2MGLLBCHESIGMAR1 | |
| SCHEMBL12040563 | 0.85 | HRH3 (0.61) | LTA4HEPHX2BCHELMNAPTGS1 | |
| SCHEMBL257764 | 0.84 | DRD2 (0.64) | FFAR1TDP1L3MBTL1DRD2DRD4 | |
| SCHEMBL11611966 | 0.84 | LMNA (0.58) | LTA4HEPHX2BCHEL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170196854-A1 | USE OF ANTHELMINTIC AGENTS AGAINST DIROFILARIA IMMITIS | INTERVET INC. (US) | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196854-A1 | USE OF ANTHELMINTIC AGENTS AGAINST DIROFILARIA IMMITIS | MPO, DHODH, DHX35 | LTA4H 149/4885EPHX2 340/4885MGLL 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.