Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000684 | 0.84 | LMNA (0.69) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8434881 | 0.81 | GSTP1 (0.58) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8616558 | 0.80 | GSTP1 (0.56) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8616159 | 0.80 | GSTP1 (0.56) | GSTP1MAOBNR4A2PARP10 | |
| SCHEMBL1574932 | 0.79 | CYP2D6 (0.44) | CYP1A2CYP2C19LTA4HRAB9ASMN1; SMN2 | |
| SCHEMBL3958235 | 0.79 | LTA4H (0.41) | LMNAPTGS2MAOBLTA4HGAA | |
| SCHEMBL8612967 | 0.79 | GSTP1 (0.55) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8614632 | 0.78 | GSTP1 (0.54) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8613858 | 0.78 | GSTP1 (0.54) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8611289 | 0.78 | GSTP1 (0.54) | GSTP1LMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483370-B1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2015-07-15 | — | — | EP | disclosed |
| US-8940184-B2 | Polymerizable compounds and their use in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| EP-2483370-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2012-08-08 | — | — | EP | disclosed |
| US-20120182516-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-07-19 | — | — | US | disclosed |
| WO-2011035842-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2011-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120182516-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS | VCL, LPXN, ACP3 | GSTP1 3965/4885LMNA 273/4885CYP1A2 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.