Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | SI | P14410 | 4/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574932 | 0.94 | CYP2D6 (0.44) | LTA4HFFAR1FFAR4RAB9ASMN1; SMN2 | |
| SCHEMBL4867819 | 0.90 | NR5A1 (0.49) | LTA4HGAAMEN1KMT2ARAB9A | |
| SCHEMBL16937461 | 0.83 | ALDH1A1 (0.37) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL9419256 | 0.82 | LTA4H (0.47) | LTA4HMGAMGAASIMGAM2 | |
| SCHEMBL9564006 | 0.81 | FFAR1 (0.47) | LTA4HGAAL3MBTL1FFAR1FFAR4 | |
| SCHEMBL26044941 | 0.80 | SMN1; SMN2 (0.44) | LTA4HKMT2AL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL9493860 | 0.80 | NR5A1 (0.53) | LTA4HL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL1461960 | 0.79 | GSTP1 (0.51) | LTA4HMGAMGAASIMGAM2 | |
| SCHEMBL9493822 | 0.79 | LMNA (0.49) | LTA4HMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL9563866 | 0.79 | RARB (0.54) | LTA4HL3MBTL1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009033532-A1 | 2,5-SELENOPHENE DERIVATIVES AND 2,5-TELLUROPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |