Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620057 | 0.76 | DRD1 (0.35) | MAOAALDH1A1TDP1MT-CO2ALOX5 | |
| SCHEMBL14620053 | 0.75 | MGLL (0.38) | MAOAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL14620181 | 0.73 | MGLL (0.48) | MAOAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL14620035 | 0.71 | CEL (0.33) | MAOA | |
| SCHEMBL14620046 | 0.69 | — | — | |
| SCHEMBL14620038 | 0.69 | CEL (0.32) | — | |
| SCHEMBL29006938 | 0.68 | ALDH1A1 (0.40) | ALDH1A1TDP1MT-CO2ALOX5MEN1 | |
| SCHEMBL14620425 | 0.66 | MT-CO2 (0.46) | ALDH1A1TDP1MT-CO2ALOX5MEN1 | |
| SCHEMBL14620182 | 0.66 | KMT2A (0.41) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL14620260 | 0.62 | CYP1B1 (0.39) | ALDH1A1ALOX5TSHRSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003520-A1 | FLUORESCENT DIKETOPYRROLOPYRROLES AND DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-01-11 | — | — | WO | disclosed |