Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.51 |
| ▸ | CTSB | P07858 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APC | P25054 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618974 | 0.94 | TACR1 (0.57) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL3827103 | 0.82 | CTSK (0.50) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL5392617 | 0.81 | ALDH1A1 (0.65) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7702259 | 0.75 | TRPM8 (0.47) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL9545976 | 0.74 | CTSL (0.69) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL9498759 | 0.74 | TRPM8 (0.47) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL329686 | 0.74 | ALDH1A1 (0.74) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7151822 | 0.74 | ALDH1A1 (0.74) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL8484509 | 0.74 | CACNA1B (0.50) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL5050481 | 0.74 | CTSK (0.52) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173039-B2 | Protein kinase inhibitors | THERAVANCE, INC. (US) | 2007-02-06 | — | — | US | disclosed |