Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.41 |
| ▸ | PANK1 | Q8TE04 | 1/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637819 | 0.82 | ALOX15 (0.42) | ALDH1A1ALOX15GAARAB9AHSD17B10 | |
| SCHEMBL1638692 | 0.82 | ALOX15 (0.42) | ALOX15GAARAB9AHSD17B10RXFP1 | |
| SCHEMBL4066238 | 0.76 | ALOX15 (0.51) | ALDH1A1ALOX15GAARAB9AHSD17B10 | |
| SCHEMBL12726405 | 0.72 | MAOB (0.39) | PANK1PANK3TSHRHTTSMN1; SMN2 | |
| SCHEMBL1639832 | 0.71 | ALOX15 (0.43) | ALOX15RAB9AHSD17B10PTGDR2TSHR | |
| SCHEMBL28709455 | 0.71 | TRPA1 (0.56) | ALDH1A1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL12479695 | 0.71 | CFD (0.50) | — | |
| SCHEMBL1638885 | 0.70 | MEN1 (0.47) | ALDH1A1GAATSHRHTT | |
| SCHEMBL1639229 | 0.70 | GAA (0.47) | ALDH1A1GAAHSD17B10TSHRHTT | |
| SCHEMBL21297851 | 0.70 | L3MBTL1 (0.42) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002293-A2 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-01-04 | — | — | WO | disclosed |