Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215818 | 0.71 | CA2 (0.39) | CA2 | |
| SCHEMBL671337 | 0.66 | LOXL2 (0.39) | — | |
| SCHEMBL29467988 | 0.66 | LOXL2 (0.39) | — | |
| SCHEMBL11688566 | 0.64 | CA1 (0.43) | CA2 | |
| SCHEMBL30007084 | 0.64 | CYP3A4 (0.38) | CA2 | |
| SCHEMBL1492048 | 0.62 | CYP2C9 (0.48) | — | |
| SCHEMBL10129554 | 0.62 | ACLY (0.44) | CA2 | |
| SCHEMBL16058359 | 0.61 | CA2 (0.45) | CA2 | |
| SCHEMBL455108 | 0.61 | SLC6A2 (0.41) | — | |
| SCHEMBL28820319 | 0.61 | RAB9A (0.48) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493865-A2 | RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | Array Biopharma, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011025938-A2 | RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2011-03-03 | — | — | WO | disclosed |