Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | DGKA | P23743 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487853 | 0.93 | KDM4E (0.55) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL1462388 | 0.93 | KDM4E (0.51) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL1462396 | 0.86 | DGKA (0.57) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL7128696 | 0.85 | MGLL (0.65) | DGKAMGLLALDH1A1ENPP2FAAH | |
| SCHEMBL5473106 | 0.81 | FFAR4 (0.46) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL16829870 | 0.81 | DGKA (0.59) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL7203853 | 0.81 | KDM4E (0.57) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL6052685 | 0.81 | DGKA (0.62) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL16800412 | 0.81 | DGKA (0.62) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL505106 | 0.81 | DGKA (0.62) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110104085-A1 | Cosmetic Or Pharmaceutical Compositions Comprising Modified Polysiloxanes With At Least One Carbamate Group | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-05-05 | — | — | US | disclosed |
| US-20050255075-A1 | Cosmetic or pharmaceutical compositions comprising modified polyorganosiloxanes | CLARIANT GMBH | 2005-11-17 | — | — | US | disclosed |
| US-6607733-B1 | Cosmetic or dermatological gels based on microemulsions | BEIERSDORF AG (DE) | 2003-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255075-A1 | Cosmetic or pharmaceutical compositions comprising modified polyorganosiloxanes | POLH, SGMS2, SGMS1 | KDM4E 1574/4885DUSP3 4703/4885MEN1 3844/4885 |
| US-20110104085-A1 | Cosmetic Or Pharmaceutical Compositions Comprising Modified Polysiloxanes With At Least One Carbamate Group | KDM1A, KDM6A, KDM2A | KDM4E 44/4885DUSP3 2994/4885MEN1 1211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.