Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14623161 | 0.77 | MYC (0.37) | MEN1POLBKMT2A | |
| SCHEMBL24696102 | 0.71 | NOS3 (0.30) | CNR1CNR2 | |
| SCHEMBL14035489 | 0.68 | DHODH (0.56) | — | |
| SCHEMBL18807848 | 0.67 | NISCH (0.39) | CNR1CNR2MEN1KMT2AALOX5 | |
| SCHEMBL14727986 | 0.65 | TRPM4 (0.33) | — | |
| SCHEMBL14231832 | 0.64 | KDM4E (0.56) | MEN1GAAKMT2A | |
| SCHEMBL6860905 | 0.63 | TRPA1 (0.46) | CNR1CNR2MEN1POLBGAA | |
| SCHEMBL12463923 | 0.61 | ELANE (0.41) | MEN1POLBGAAKMT2A | |
| SCHEMBL2399470 | 0.59 | CNR1 (0.48) | CNR1CNR2MEN1POLBGAA | |
| SCHEMBL5541764 | 0.59 | HSD17B10 (0.49) | CNR1CNR2MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001406-A2 | ARYL-CONTAINING MACROCYCLIC COMPOUNDS | CHIRON CORPORATION (US) | 2007-01-04 | — | — | WO | disclosed |