SCHEMBL3821101

SCHEMBL3821101

NNC(CC(N)=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 2/20 0.46
ITGB2 P05107 2/20 0.43
ICAM1 P05362 2/20 0.43
ITGAL P20701 2/20 0.43
CA2 P00918 5/20 0.41
CA1 P00915 4/20 0.41
ALDH1A1 P00352 2/20 0.41
RAB9A P51151 1/20 0.41
GNPAT O15228 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TGFBR1 P36897 1/20 0.40
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3469298 1.00 ECE1 (0.46) ECE1ITGB2ICAM1ITGALCA2
Water SCHEMBL31495128 0.98 ECE1 (0.44) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL14071766 0.83 ECE1 (0.44) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL22106724 0.83 ECE1 (0.44) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL14625014 0.82 GNPAT (0.51) CA2CA1GNPAT
SCHEMBL8601335 0.82 ECE1 (0.47) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL7080110 0.82 GNPAT (0.51) CA2CA1GNPAT
SCHEMBL6558713 0.82 GNPAT (0.51) CA2CA1GNPAT
SCHEMBL29742771 0.82 ECE1 (0.47) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL1009371 0.80 ECE1 (0.50) ECE1ITGB2ICAM1ITGALCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210115156-A1 FC-ENGINEERED ANTI-HUMAN IGE ANTIBODIES AND METHODS OF USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2021-04-22 US claimed
EP-3774925-A1 FC-ENGINEERED ANTI-HUMAN IGE ANTIBODIES AND METHODS OF USE Institut national de la santé et de la recherche médicale (INSERM) (FR) 2021-02-17 EP claimed
WO-2019197607-A1 FC-ENGINEERED ANTI-HUMAN IGE ANTIBODIES AND METHODS OF USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2019-10-17 WO claimed
CN-108064271-A Methylotrophic Bacillus strain and the method that plant drought resistance is improved using the bacterial strain 皇家学术促进会麦吉尔大学 2018-05-22 CN claimed
US-20170226598-A1 A BACILLUS METHYLOTROPHICUS STRAIN AND METHOD OF USING THE STRAIN TO INCREASE DROUGHT RESISTANCE IN A PLANT THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2017-08-10 US claimed
EP-3191579-A1 A BACILLUS METHYLOTROPHICUS STRAIN AND METHOD OF USING THE STRAIN TO INCREASE DROUGHT RESISTANCE IN A PLANT The Royal Institution for the Advancement of Learning / McGill University (CA) 2017-07-19 EP claimed
WO-2016011562-A1 A BACILLUS METHYLOTROPHICUS STRAIN AND METHOD OF USING THE STRAIN TO INCREASE DROUGHT RESISTANCE IN A PLANT THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2016-01-28 WO claimed
CN-103374058-A Solid-phase synthesis process of angiotensinamide as well as intermediate and application thereof SHANGHAI NO 1 BIOCHEMICAL & PHARMACEUTICAL CO LTD 2013-10-30 CN claimed
US-20240076410-A1 FC-ENGINEERED ANTI-HUMAN IGE ANTIBODIES AND METHODS OF USE INSTITUT PASTEUR (FR) 2024-03-07 US disclosed
US-20210115156-A1 FC-ENGINEERED ANTI-HUMAN IGE ANTIBODIES AND METHODS OF USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2021-04-22 US disclosed
EP-3774925-A1 FC-ENGINEERED ANTI-HUMAN IGE ANTIBODIES AND METHODS OF USE Institut national de la santé et de la recherche médicale (INSERM) (FR) 2021-02-17 EP disclosed
WO-2020244570-A1 PORPHIN PHOTOSENSITIZER TARGETING FOLIC ACID AND COUPLED TO DIFFERENT CONNECTION CHAINS AND SYNTHESIS AND APPLICATION OF PORPHIN PHOTOSENSITIZER 康宏耀源(天津)科技有限公司 2020-12-10 WO disclosed
CN-110462038-A Anti- GPRC5D antibody and the molecule comprising the antibody DAIICHI SANKYO CO LTD 2019-11-15 CN disclosed
WO-2019197607-A1 FC-ENGINEERED ANTI-HUMAN IGE ANTIBODIES AND METHODS OF USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2019-10-17 WO disclosed
EP-1571919-B2 NOVEL FOOD PRODUCTION PROCESS DSM IP ASSETS BV (NL) 2015-04-15 EP disclosed
CN-103374058-B Solid-phase synthesis process of angiotensinamide as well as intermediate and application thereof SHANGHAI NO 1 BIOCHEMICAL & PHARMACEUTICAL CO LTD 2015-04-15 CN disclosed
CN-103374058-A Solid-phase synthesis process of angiotensinamide as well as intermediate and application thereof SHANGHAI NO 1 BIOCHEMICAL & PHARMACEUTICAL CO LTD 2013-10-30 CN disclosed
CN-102241743-A Process for producing sugar peptide having asparagine sugar chain and the sugar peptide OTSUKA CHEMICAL CO LTD 2011-11-16 CN disclosed
EP-1571919-B1 NOVEL FOOD PRODUCTION PROCESS DSM IP ASSETS BV (NL) 2009-08-26 EP disclosed
CN-1665832-A Process for producing glycopeptide having asparagine sugar chain and glycopeptide OTSUKA CHEMICAL CO LTD (JP) 2005-09-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170226598-A1 A BACILLUS METHYLOTROPHICUS STRAIN AND METHOD OF USING THE STRAIN TO INCREASE DROUGHT RESISTANCE IN A PLANT AMD1, AHCY, ALAD ECE1 962/4885ITGB2 4836/4885ICAM1 4618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.