Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1055347 | 0.83 | GABRA1 (0.56) | GABRA1GABRB2ALOX5CNR2POLB | |
| SCHEMBL29414940 | 0.83 | GABRA1 (0.56) | GABRA1GABRB2ALOX5CNR2POLB | |
| SCHEMBL29463283 | 0.83 | GABRA1 (0.56) | GABRA1GABRB2ALOX5CNR2POLB | |
| SCHEMBL14626465 | 0.80 | GABRA1 (0.48) | GABRA1GABRB2ALOX5CNR2TRPM8 | |
| SCHEMBL14626463 | 0.79 | GABRA1 (0.38) | GABRA1GABRB2ALOX5CNR2ALDH1A1 | |
| SCHEMBL2300766 | 0.78 | ESR1 (0.53) | GABRA1GABRB2ALOX5CNR2POLB | |
| 2-Allylphenol SCHEMBL22207670 | 0.76 | GABRA1 (0.49) | GABRA1GABRB2ALOX5CNR2POLB | |
| SCHEMBL16255461 | 0.74 | PTGDR (0.41) | GABRA1GABRB2CNR2ALDH1A1CNR1 | |
| SCHEMBL8417779 | 0.73 | GABRA1 (0.51) | GABRA1GABRB2ALOX5CNR2TRPM8 | |
| SCHEMBL21192545 | 0.73 | ALOX5 (0.32) | GABRA1GABRB2ALOX5CNR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163986-B2 | Siloxane copolymer, making method, and thermosetting resin composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |