Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25946547 | 0.85 | REN (0.39) | RENCTSDBACE1FOLH1GABRP | |
| SCHEMBL15846434 | 0.76 | FOLH1 (0.62) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL15846435 | 0.76 | FOLH1 (0.62) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL25745409 | 0.76 | FOLH1 (0.44) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14628587 | 0.74 | TSHR (0.41) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21150988 | 0.74 | FOLH1 (0.47) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17948386 | 0.74 | FOLH1 (0.46) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9830238 | 0.73 | ADAMTS4 (0.37) | CTSD | |
| SCHEMBL18756332 | 0.73 | GABRP (0.45) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL25946467 | 0.72 | BMP1 (0.60) | RENCTSDBACE1FOLH1RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781554-B1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FOER MEDICINSK FORSKNING (SE) | 2023-06-28 | — | — | EP | disclosed |