Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 5/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16260527 | 0.82 | RAPGEF4 (0.36) | POLBALDH1A1MAPTMEN1GAA | |
| SCHEMBL12807692 | 0.79 | ESR1 (0.34) | — | |
| SCHEMBL2018161 | 0.79 | POLB (0.50) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL896031 | 0.79 | POLB (0.50) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL26223508 | 0.78 | ALDH1A1 (0.48) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL12705758 | 0.75 | POLB (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL2022116 | 0.75 | POLB (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL3231058 | 0.72 | CYP2A6 (0.39) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL11613649 | 0.71 | ALDH1A1 (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| Fluoride SCHEMBL1334652 | 0.70 | CYP2A6 (0.38) | GABRA1GABRB2TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1741740-A1 | POLYMER HAVING OXOCARBON GROUP AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2007-01-10 | — | — | EP | disclosed |