Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 4/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3231058 | 0.97 | CYP2A6 (0.39) | CYP2A6CYP1A2SCN4ATRPA1ATM | |
| SCHEMBL16707482 | 0.75 | SMN1; SMN2 (0.38) | CYP2A6CYP1A2SCN4ATRPA1ATM | |
| SCHEMBL30571175 | 0.73 | TXN (0.36) | CYP2A6CYP1A2SCN4ATRPA1ATM | |
| SCHEMBL16260527 | 0.72 | RAPGEF4 (0.36) | CYP2A6CYP1A2ALDH1A1CA2SMN1; SMN2 | |
| SCHEMBL13494352 | 0.70 | ACHE (0.35) | ACHESLC6A4 | |
| SCHEMBL14629628 | 0.70 | POLB (0.46) | ATMGABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL10351674 | 0.70 | CYP1A2 (0.38) | CYP2A6CYP1A2TSHRALDH1A1SLC6A4 | |
| SCHEMBL7930508 | 0.70 | ACHE (0.43) | CYP2A6CYP1A2TRPA1ATMGABRA1 | |
| SCHEMBL19860980 | 0.70 | CA2 (0.48) | GABRA1GABRB2TSHRALDH1A1CA2 | |
| SCHEMBL29044217 | 0.70 | ESR1 (0.39) | TRPA1ATMTSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12522682-B2 | Synthesis of methyl 2-fluoroacrylate | VIFOR (INTERNATIONAL) LTD. (CH) | 2026-01-13 | — | — | US | claimed |
| EP-4229033-A1 | PROCESSES OF PREPARING 3-FLUORO-5-(((1S,2AR)-1,3,3,4,4-PENTAFLUORO-2A-HYDROXY-2,2A,3,4-TETRAHYDRO-1H-CYCLOPENTA[CD]INDEN-7-YL)OXY)-BENZONITRILE | Nikang Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | claimed |
| US-20230202970-A1 | PROCESS OF PREPARING 3-FLUORO-5(((1R,2AR)-3,3,4,4-TETRAFLUORO-1,2A-DIHYDROXY-2,2A,3,4-TETRAHYDRO-1H-CYCLOPENTA[CD]INDEN-7-YL)-OXY)BENZONITRILE | NIKANG THERAPEUTIC INC (US) | 2023-06-29 | — | — | US | claimed |
| US-20230126376-A1 | SYNTHESIS OF METHYL 2-FLUOROACRYLATE | VIFOR (INTERNATIONAL) LTD. (CH) | 2023-04-27 | — | — | US | claimed |
| US-11634382-B2 | Process of preparing 3-fluoro-5(((1R,2aR)-3,3,4,4-tetrafluoro-1,2a-dihydroxy-2,2a,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)-oxy)benzonitrile | NIKANG THERAPEUTICS, INC. (US) | 2023-04-25 | — | — | US | claimed |
| WO-2023050975-A1 | α-FLUOROACYL PIPERAZINE DERIVATIVE, AND PREPARATION AND APPLICATION THEREOF | 云白药征武科技(上海)有限公司 | 2023-04-06 | — | — | WO | claimed |
| EP-4126807-A1 | SYNTHESIS OF METHYL 2-FLUOROACRYLATE | Vifor (International) Ltd. (CH) | 2023-02-08 | — | — | EP | claimed |
| WO-2022235536-A1 | ATOMIC LAYER DEPOSITION OF METAL FLUORIDE FILMS | APPLIED MATERIALS, INC. (US) | 2022-11-10 | — | — | WO | claimed |
| US-20220351960-A1 | Atomic Layer Deposition Of Metal Fluoride Films | APPLIED MATERIALS, INC. (US) | 2022-11-03 | — | — | US | claimed |
| CN-109535025-B | Preparation method of Evonib intermediate 3, 3-difluorocyclobutylamine hydrochloride | 尚科生物医药（上海）有限公司 | 2022-09-09 | — | — | CN | claimed |
| US-20170283960-A1 | METHOD OF DISCOVERING FLUORO-CONTAINING COMPOUNDS | SHANXI CHEMICAL RESEARCH INSTITUTE CO., LTD. (CN) | 2017-10-05 | — | — | US | claimed |
| EP-2812311-B1 | PROCESSES FOR ISOLATING FLUORINATED PRODUCTS | UBE INDUSTRIES (JP) | 2016-04-20 | — | — | EP | claimed |
| US-8937204-B1 | Processes for isolating fluorinated products | UBE INDUSTRIES, LTD. (JP) | 2015-01-20 | — | — | US | claimed |
| EP-2812311-A1 | PROCESSES FOR ISOLATING FLUORINATED PRODUCTS | UBE Industries, Ltd. (JP) | 2014-12-17 | — | — | EP | claimed |
| US-20140046086-A1 | PROCESS FOR THE PREPARATION OF TAFLUPROST AND INTERMEDIATES THEREOF | SCINOPHARM (CHANGSHU) PHARMACEUTICALS, LTD. (CN) | 2014-02-13 | — | — | US | claimed |
| WO-2013118915-A1 | PROCESSES FOR ISOLATING FLUORINATED PRODUCTS | UBE INDUSTRIES, LTD. (JP) | 2013-08-15 | — | — | WO | claimed |
| US-8203003-B2 | 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods | UBE INDUSTRIES, LTD. (JP) | 2012-06-19 | — | — | US | claimed |
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | UBE INDUSTRIES, LTD. (JP) | 2011-11-10 | — | — | US | claimed |
| WO-2010081014-A1 | NOVEL 4-FLUOROPYRROLIDINE-2-CARBONYL FLUORIDE COMPOUNDS AND THEIR PREPARATIVE METHODS | IM&T RESEARCH, INC. (US) | 2010-07-15 | — | — | WO | claimed |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | IM&T RESEARCH, INC. (US) | 2010-07-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230126376-A1 | SYNTHESIS OF METHYL 2-FLUOROACRYLATE | PFAS, FOLR1, MFAP1 | CYP2A6 2542/4885CYP1A2 2360/4885SCN4A 2378/4885 |
| US-11634382-B2 | Process of preparing 3-fluoro-5(((1R,2aR)-3,3,4,4-tetrafluoro-1,2a-dihydroxy-2,2a,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)-oxy)benzonitrile | CYP4B1, CYP1B1, CYP3A4 | CYP2A6 109/4885CYP1A2 18/4885SCN4A 308/4885 |
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | PFAS, AFF4, PAICS | CYP2A6 3084/4885CYP1A2 2348/4885SCN4A 1354/4885 |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | QDPR, FDPS, DPYD | CYP2A6 989/4885CYP1A2 584/4885SCN4A 2471/4885 |
| US-20230202970-A1 | PROCESS OF PREPARING 3-FLUORO-5(((1R,2AR)-3,3,4,4-TETRAFLUORO-1,2A-DIHYDROXY-2,2A,3,4-TETRAHYDRO-1H-CYCLOPENTA[CD]INDEN-7-YL)-OXY)BENZONITRILE | CYP4B1, CYP1B1, CYP3A4 | CYP2A6 109/4885CYP1A2 18/4885SCN4A 308/4885 |
| US-20140046086-A1 | PROCESS FOR THE PREPARATION OF TAFLUPROST AND INTERMEDIATES THEREOF | PTGIS, PTGES, PTGES3 | CYP2A6 50/4885CYP1A2 68/4885SCN4A 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.