Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTR1D | P28221 | 5/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613649 | 0.85 | ALDH1A1 (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL896031 | 0.83 | POLB (0.50) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL12705758 | 0.79 | POLB (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL2022116 | 0.79 | POLB (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL14629628 | 0.79 | POLB (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL3818856 | 0.75 | CYP2C9 (0.47) | POLBGABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL24344713 | 0.74 | POLB (0.41) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL9935610 | 0.73 | RAPGEF4 (0.43) | TSHRALDH1A1TDP1HSD17B10TP53 | |
| SCHEMBL8664743 | 0.73 | POLB (0.57) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL93161 | 0.71 | GABRA1 (0.69) | POLBHTR1DGABRA1GABRB2HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160488-A1 | Fluorination Processes with Arylsulfur Halotetrafluorides | I M &T RESEARCH, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| WO-2009114409-A2 | FLUORINATION PROCESSES WITH ARYLSULFUR HALOTETRAFLUORIDES | IM & T RESEARCH, INC. (US) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160488-A1 | Fluorination Processes with Arylsulfur Halotetrafluorides | CYP2F1, PFAS, CYP4F2 | POLB 2365/4885HTR1D 2309/4885GABRA1 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.