Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 5/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896031 | 0.79 | POLB (0.50) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL2018161 | 0.79 | POLB (0.50) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL896127 | 0.76 | RAPGEF4 (0.39) | TSHRALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL2022116 | 0.75 | POLB (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL14629628 | 0.75 | POLB (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL6353240 | 0.72 | CYP3A4 (0.46) | ALDH1A1ALOX15TDP1MEN1GAA | |
| SCHEMBL11613649 | 0.71 | ALDH1A1 (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL1847884 | 0.70 | POLB (0.52) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL24344713 | 0.70 | POLB (0.41) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL8664743 | 0.69 | POLB (0.57) | POLBHTR1DGABRA1GABRB2HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919635-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| US-20090203924-A1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM&T RESEARCH, INC. (US) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203924-A1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | PFAS, FRS2, FBL | POLB 2510/4885HTR1D 3436/4885GABRA1 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.