Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777302 | 0.89 | DHODH (0.37) | HIF1AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7784037 | 0.86 | MAPT (0.38) | HIF1AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5550206 | 0.84 | MEN1 (0.35) | MAPTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7785460 | 0.84 | MAPT (0.39) | HIF1AMAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL5549293 | 0.83 | MAPT (0.39) | MAPTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7784131 | 0.83 | MAPT (0.39) | MAPTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL891063 | 0.82 | LRP6 (0.33) | MAPTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL12610521 | 0.81 | MAPT (0.34) | HIF1AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15693690 | 0.81 | DHODH (0.35) | HIF1AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7473791 | 0.81 | NPC1 (0.33) | MAPTNPC1SMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975619-B1 | INTENSE COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b] PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LTD (GB) | 2007-01-03 | — | — | EP | disclosed |