SCHEMBL14629803

SCHEMBL14629803

CCCCCCCCCCCCCCCCCC(=O)C(C(=O)CCCCCCCCCCCCCCCCC)(C(N)O)P(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 8/20 0.46
▸ CES1 P23141 5/20 0.46
▸ CES2 O00748 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ FDPS P14324 4/20 0.43
▸ SMPD1 P17405 2/20 0.43
▸ LAP3 P28838 1/20 0.43
▸ GGPS1 O95749 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16493550 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL5907428 0.79 FAAH (0.52) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2783090 0.73 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL25868 0.73 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2782415 0.73 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL466673 0.73 SMPD1 (0.44) FAAHCES1CES2MEN1CYP1A2
SCHEMBL466582 0.73 SMPD1 (0.44) FAAHCES1CES2MEN1CYP1A2
SCHEMBL466941 0.73 SMPD1 (0.44) FAAHCES1CES2MEN1CYP1A2
SCHEMBL466752 0.73 SMPD1 (0.44) FAAHCES1CES2MEN1CYP1A2
Phosphoric Acid SCHEMBL5312301 0.73 FAAH (0.53) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12569439-B2 Bottom-up assembly of synthetic extracellular vesicles MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2026-03-10 — — US disclosed
US-20250257409-A1 COMPOSITIONS AND METHODS FOR THERAPEUTICS PRESCREENING TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2025-08-14 — — US disclosed
US-12344899-B2 Compositions and methods for therapeutics prescreening TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2025-07-01 — — US disclosed
CN-120022383-A Nucleic acid medicine for mediating cell pyrosis and application thereof 上海交通大学 2025-05-23 — — CN disclosed
CN-119732913-A Lipid nanoparticle freeze-dried preparation and preparation method and application thereof 荣灿生物医药技术(上海)有限公司 2025-04-01 — — CN disclosed
CN-118319880-B Lipid nanoparticle for targeted lung efficient delivery of nucleic acid, inhalation formulation and application 荣灿生物医药技术(上海)有限公司 2025-02-07 — — CN disclosed
CN-118255678-B Ionizable lipid compound and application thereof 荣灿生物医药技术(上海)有限公司 2024-12-24 — — CN disclosed
US-20230364270-A1 LIPOSOME-ASSISTED IMAGING OF VASCULAR INFLAMMATION HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ (FI) 2023-11-16 — — US disclosed
US-11788146-B2 Methods for therapeutics prescreening in bodily fluids BARCODE DIAGNOSTICS LTD. (IL) 2023-10-17 — — US disclosed
US-20230181466-A1 BOTTOM-UP ASSEMBLY OF SYNTHETIC EXTRACELLULAR VESICLES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-06-15 — — US disclosed
US-20160220710-A1 COMPOSITIONS AND METHODS FOR DELIVERING PHARMACEUTICAL AGENTS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2016-08-04 — — US disclosed
US-9339462-B2 Lipid vesicle compositions and methods of use MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-05-17 — — US disclosed
WO-2016024281-A1 COMPOSITIONS AND METHODS FOR THERAPEUTICS PRESCREENING TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED. (IL) 2016-02-18 — — WO disclosed
US-20160038415-A1 LIPID VESICLE COMPOSITIONS AND METHODS OF USE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-02-11 — — US disclosed
US-20150272884-A1 LIPID VESICLE COMPOSITIONS AND METHODS OF USE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-10-01 — — US disclosed
US-8951542-B2 Lipid vesicle compositions and methods of use MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-02-10 — — US disclosed
US-20140271827-A1 LIPID VESICLE COMPOSITIONS AND METHODS OF USE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-09-18 — — US disclosed
EP-2547327-A2 LIPID VESICLE COMPOSITIONS AND METHODS OF USE Massachusetts Institute of Technology (US) 2013-01-23 — — EP disclosed
CN-101805369-B Preparation methods of distearoyl phosphatidyl ethanolamine and amino polyethylene glycol derivatives thereof UNIV SOUTHEAST 2012-10-03 — — CN disclosed
CN-101805369-A Preparation methods of distearoyl phosphatidyl ethanolamine and amino polyethylene glycol derivatives thereof UNIV SOUTHEAST 2010-08-18 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140271827-A1 LIPID VESICLE COMPOSITIONS AND METHODS OF USE CHMP4B, LIPA, SGMS2 FAAH 889/4885CES1 949/4885CES2 1251/4885
US-20150272884-A1 LIPID VESICLE COMPOSITIONS AND METHODS OF USE CHMP4B, LIPA, SGMS2 FAAH 889/4885CES1 949/4885CES2 1251/4885
US-20160220710-A1 COMPOSITIONS AND METHODS FOR DELIVERING PHARMACEUTICAL AGENTS MSR1, CD68, SLC11A2 FAAH 1939/4885CES1 516/4885CES2 550/4885
US-20160038415-A1 LIPID VESICLE COMPOSITIONS AND METHODS OF USE CHMP4B, ANXA5, CD63 FAAH 1226/4885CES1 1462/4885CES2 1391/4885
US-12569439-B2 Bottom-up assembly of synthetic extracellular vesicles EXOSC10, PLTP, EXOSC9 FAAH 1698/4885CES1 3436/4885CES2 4020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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