SCHEMBL466673

SCHEMBL466673

CCCCCCCCCCCCCCCCCC(=O)C(O)C(N)(C(=O)CCCCCCCCCCCCCCCCC)P(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SMPD1 P17405 2/20 0.44
▸ FDPS P14324 1/20 0.44
▸ FAAH O00519 6/20 0.42
▸ CES1 P23141 4/20 0.42
▸ CES2 O00748 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466941 1.00 SMPD1 (0.44) SMPD1FDPSFAAHCES1CES2
SCHEMBL466582 1.00 SMPD1 (0.44) SMPD1FDPSFAAHCES1CES2
SCHEMBL466752 1.00 SMPD1 (0.44) SMPD1FDPSFAAHCES1CES2
SCHEMBL466809 0.98 FDPS (0.42) SMPD1FDPSFAAHCES1CES2
SCHEMBL466712 0.92 FAAH (0.51) FAAHCES1CES2MEN1CYP1A2
SCHEMBL466646 0.92 FAAH (0.51) FAAHCES1CES2MEN1CYP1A2
SCHEMBL466851 0.92 FAAH (0.51) FAAHCES1CES2MEN1CYP1A2
SCHEMBL466745 0.89 KDM4E (0.55) FAAHCES1MEN1CYP1A2KMT2A
SCHEMBL18092236 0.75 CES2 (0.52) FAAHCES1CES2MEN1KMT2A
SCHEMBL10824505 0.74 LPAR3 (0.46) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180258113-A1 NOVEL ARTIFICIAL PHOSPHOLIPID-PROTEIN BIOCONJUGATES FOR BIOMOLECULAR RECOGNITION ASTAKHOVA, Irina Kira (DK) 2018-09-13 — — US claimed
WO-2015055630-A1 COMPOSITIONS FOR TRANSFECTING NUCLEIC ACID MOLECULES INTO EUKARYOTIC CELLS TECHNISCHE UNIVERSITÄT GRAZ (AT) 2015-04-23 — — WO claimed
EP-2860255-A1 Compositions comprising cationic and neutral lipids for transfecting nucleic acid molecules into eukaryotic cells Technische Universität Graz (AT) 2015-04-15 — — EP claimed
US-20220296518-A1 LIPID-BASED NANOPARTICLE DELIVERY SYSTEM FOR HYDROPHILIC CHARGED COMPOUND NATIONAL TAIWAN UNIVERSITY (TW) 2022-09-22 — — US disclosed
US-20200197306-A1 CATIONIC LIQUID CRYSTALLINE NANOPARTICLES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-06-25 — — US disclosed
WO-2019078611-A1 NANOLIPOSOME-MICROBUBBLE CONJUGATE HAVING CAS9 PROTEIN, GUIDE RNA FOR INHIBITING EXPRESSION OF SRD5A2 GENE AND CATIONIC POLYMER COMPLEX ENCAPSULATED THEREIN, AND HAIR LOSS RELIEVING OR TREATING COMPOSITION CONTAINING SAME 주식회사 무진메디 2019-04-25 — — WO disclosed
US-20180258113-A1 NOVEL ARTIFICIAL PHOSPHOLIPID-PROTEIN BIOCONJUGATES FOR BIOMOLECULAR RECOGNITION ASTAKHOVA, Irina Kira (DK) 2018-09-13 — — US disclosed
US-9315828-B2 Prompt nucleic acid delivery carrier composition Takeuchi, Hirofumi (JP) 2016-04-19 — — US disclosed
US-9090912-B1 Nucleic acid complex and nucleic acid-delivering composition Takeuchi, Hirofumi (JP) 2015-07-28 — — US disclosed
EP-2405001-B1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID-DELIVERING COMPOSITION TAKEUCHI HIROFUMI (JP) 2015-07-08 — — EP disclosed
EP-2140870-B1 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION OTSUKA PHARMA CO LTD (JP) 2015-06-24 — — EP disclosed
EP-2217208-B1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION OTSUKA PHARMA CO LTD (JP) 2011-08-31 — — EP disclosed
US-20100305190-A1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION Takeuchi, Hirofumi (JP) 2010-12-02 — — US disclosed
EP-2217208-A2 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION Otsuka Pharmaceutical Co., Ltd. (JP) 2010-08-18 — — EP disclosed
US-20100063131-A1 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION Takeuchi, Hirofumi (JP) 2010-03-11 — — US disclosed
US-20100034749-A1 Use of a Cationic Collodal Preparation for the Diagnosis and Treatment of Ocular Diseases MEDIGENE AG (DE) 2010-02-11 — — US disclosed
EP-2140870-A1 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION Otsuka Pharmaceutical Co., Ltd. (JP) 2010-01-06 — — EP disclosed
US-20090258923-A1 Carrier Composition for Nucleic Acid Transport OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-10-15 — — US disclosed
WO-2009061003-A2 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-05-14 — — WO disclosed
EP-1946761-A1 CARRIER COMPOSITION FOR NUCLEIC ACID TRANSPORT Otsuka Pharmaceutical Co., Ltd. (JP) 2008-07-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180258113-A1 NOVEL ARTIFICIAL PHOSPHOLIPID-PROTEIN BIOCONJUGATES FOR BIOMOLECULAR RECOGNITION PEBP1, PLTP, PHOSPHO1 SMPD1 53/4885FDPS 2395/4885FAAH 2285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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