Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Ethylhexanoic Acid SCHEMBL4018852 | 0.93 | CA2 (0.43) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL28527848 | 0.86 | THRB (0.62) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL1463076 | 0.86 | THRB (0.62) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL910634 | 0.84 | TDP1 (0.62) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL1548518 | 0.83 | TDP1 (0.60) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL27805505 | 0.82 | TDP1 (0.55) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL344148 | 0.82 | TDP1 (0.55) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL4657863 | 0.82 | TDP1 (0.55) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL5653025 | 0.81 | THRB (0.44) | THRBATMTDP1TAS1R3TAS1R1 | |
| Cinnamic Acid SCHEMBL16972733 | 0.81 | TDP1 (0.57) | THRBATMTDP1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417162-B2 | Oily ingredient for cosmetic preparation and cosmetic preparation | KYOWA YUKA CO., LTD. (JP) | 2008-08-26 | — | — | US | claimed |
| US-20220334130-A1 | MELANOGENESIS DETECTION METHOD USING FAM86A | Research & Business Foundation Sungkyunkwan University (KR) | 2022-10-20 | — | — | US | disclosed |
| US-7417162-B2 | Oily ingredient for cosmetic preparation and cosmetic preparation | KYOWA YUKA CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20080119551-A1 | SKIN COSMETICS COMPRISING A CYSTINE DERIVATIVE AND A CHEMICAL PEELING AGENT, A BACTERICIDE, AN ANIONIC SUFACTANT, OR A CATIONIC SURFACTANT | AJINOMOTO CO. INC (JP) | 2008-05-22 | — | — | US | disclosed |
| US-20040219178-A1 | Oily ingredient for cosmetic preparation and cosmetic preparation | KYOWA YUKA CO., LTD. (JP) | 2004-11-04 | — | — | US | disclosed |
| US-20040156802-A1 | Cosmetics or external preparations for skin | AJINOMOTO CO., INC. (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-0419148-B2 | Cosmetic composition | SHISEIDO CO LTD (JP) | 2004-06-30 | — | — | EP | disclosed |
| EP-1426041-A1 | OILY INGREDIENT FOR COSMETIC PREPARATION AND COSMETIC PREPARATION | Kyowa Yuka Co., Ltd. (JP) | 2004-06-09 | — | — | EP | disclosed |
| EP-1374831-A1 | COMSETICS OR EXTERNAL PREPARAIOTNS FOR SKIN | Ajinomoto Co., Inc. (JP) | 2004-01-02 | — | — | EP | disclosed |
| EP-0419148-B1 | Cosmetic composition | SHISEIDO CO LTD (JP) | 1995-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040156802-A1 | Cosmetics or external preparations for skin | CUTA, PSAP, CTH | THRB 4355/4885ATM 3041/4885TDP1 3983/4885 |
| US-20040219178-A1 | Oily ingredient for cosmetic preparation and cosmetic preparation | DEGS1, DAGLA, LBR | THRB 3332/4885ATM 3628/4885TDP1 1421/4885 |
| US-20080119551-A1 | SKIN COSMETICS COMPRISING A CYSTINE DERIVATIVE AND A CHEMICAL PEELING AGENT, A BACTERICIDE, AN ANIONIC SUFACTANT, OR A CATIONIC SURFACTANT | CUTA, CTH, SRM | THRB 4746/4885ATM 3124/4885TDP1 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.