Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463154 | 0.90 | MAPT (0.43) | MAPTKDM4ETHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL1462908 | 0.89 | GPR119 (0.44) | MAPTKDM4ETHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL1726675 | 0.83 | GPR174 (0.38) | MAPTSMN1; SMN2ALDH1A1LMNAGPR174 | |
| SCHEMBL1462909 | 0.82 | KDM4E (0.48) | MAPTKDM4ETHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL1420920 | 0.82 | GPR119 (0.44) | MAPTKDM4ETHRBALDH1A1LMNA | |
| SCHEMBL1082361 | 0.78 | GPR119 (0.46) | MAPTKDM4ETHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL28651590 | 0.78 | NAMPT (0.47) | MAPTKDM4ETHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL24582171 | 0.77 | MAPT (0.46) | MAPTKDM4ETHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL1420930 | 0.76 | GPR119 (0.52) | MAPTKDM4ETHRBALDH1A1LMNA | |
| SCHEMBL24480736 | 0.75 | GPR174 (0.54) | MAPTSMN1; SMN2ALDH1A1LMNAGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518971-B2 | Insecticidal phenyl- or pyridyl-piperdine compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-8193362-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-06-05 | — | — | US | disclosed |
| US-20110136866-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERDINE COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110071191-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071191-A1 | INSECTICIDAL COMPOUNDS | CBR3, CBR1, ACHE | MAPT 4567/4885KDM4E 1894/4885THRB 3113/4885 |
| US-20110136866-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERDINE COMPOUNDS | ACHE, CHRM1, CHRM2 | MAPT 3185/4885KDM4E 1079/4885THRB 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.