Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | HTT | P42858 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420738 | 0.88 | GPR174 (0.37) | GPR174ALDH1A1HTTLMNAMAPT | |
| SCHEMBL1420688 | 0.86 | CYP2C9 (0.39) | ALDH1A1MAPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL1463152 | 0.83 | MAPT (0.45) | GPR174ALDH1A1HTTLMNAMAPT | |
| SCHEMBL1463154 | 0.72 | MAPT (0.43) | GPR174ALDH1A1HTTLMNAMAPT | |
| SCHEMBL1462908 | 0.72 | GPR119 (0.44) | ALDH1A1HTTLMNAMAPTHPGD | |
| SCHEMBL21986291 | 0.71 | HCAR3 (0.50) | GPR174ALDH1A1HTTLMNAMAPT | |
| SCHEMBL17844433 | 0.69 | GRM2 (0.38) | — | |
| SCHEMBL1865742 | 0.69 | SRD5A2 (0.41) | GPR174ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1303713 | 0.68 | PDE10A (0.39) | CYP2C9 | |
| SCHEMBL12485845 | 0.67 | GPR119 (0.43) | GPR174ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037282-A3 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| EP-2324010-B1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-11-30 | — | — | EP | disclosed |