Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14633780 | 0.82 | CA12 (0.35) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14634363 | 0.79 | ALDH1A1 (0.47) | CA12CA1CA2CA9CA14 | |
| SCHEMBL27512738 | 0.73 | GRM6 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL946381 | 0.72 | CA12 (0.36) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14633892 | 0.72 | KDM4E (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL27681078 | 0.68 | GRM6 (0.42) | CA12CA1CA2CA9CA14 | |
| SCHEMBL1028144 | 0.67 | ALOX15 (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL2403279 | 0.67 | MAPT (0.47) | GRM6ALOX15KDM4EALDH1A1GAA | |
| SCHEMBL11090176 | 0.66 | ALOX15 (0.53) | CA12CA1CA2CA9CA14 | |
| SCHEMBL27503211 | 0.66 | GRM6 (0.50) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842944-B1 | METHOD FOR PRODUCING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | NIPPON SODA CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| EP-2557078-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NIPPON SODA CO (JP) | 2016-03-23 | — | — | EP | disclosed |
| EP-2730561-B1 | Methods to prepare haloalkyl nitrogen-containing heterocyclic compounds | NIPPON SODA CO (JP) | 2015-10-14 | — | — | EP | disclosed |
| US-8981107-B2 | Nitrogen-containing heterocyclic compound and method for producing same | NIPPON SODA CO., LTD. (JP) | 2015-03-17 | — | — | US | disclosed |
| EP-2842944-A1 | Method for producing nitrogen-containing heterocyclic compound | NIPPON SODA CO., LTD. (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-8962850-B2 | Nitrogen-containing heterocyclic compound and method for producing same | NIPPON SODA CO., LTD. (JP) | 2015-02-24 | — | — | US | disclosed |
| US-8962849-B2 | Nitrogen-containing heterocyclic compound and method for producing same | NIPPON SODA CO., LTD. (JP) | 2015-02-24 | — | — | US | disclosed |
| US-8809544-B2 | Nitrogen-containing heterocyclic compound and method for producing same | NIPPON SODA CO., LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20140194629-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NIPPON SODA CO., LTD. (JP) | 2014-07-10 | — | — | US | disclosed |
| US-20140171651-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NIPPON SODA CO., LTD. (JP) | 2014-06-19 | — | — | US | disclosed |
| US-20140163235-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NIPPON SODA CO., LTD. (JP) | 2014-06-12 | — | — | US | disclosed |
| US-20140155616-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NIPPON SODA CO., LTD. (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2730561-A1 | Methods to prepare nitrogen-containing heterocyclic compounds | NIPPON SODA CO., LTD. (JP) | 2014-05-14 | — | — | EP | disclosed |
| US-8703959-B2 | Nitrogen-containing heterocyclic compound and method for producing same | NIPPON SODA CO., LTD (JP) | 2014-04-22 | — | — | US | disclosed |
| EP-2557078-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | Nippon Soda Co., Ltd. (JP) | 2013-02-13 | — | — | EP | disclosed |
| US-20130023664-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NIPPON SODA CO., LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163235-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NOS1, NOS2, NOS3 | CA12 4088/4885CA1 1871/4885CA2 2523/4885 |
| US-20140171651-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NOS1, NOS2, NOS3 | CA12 4088/4885CA1 1871/4885CA2 2523/4885 |
| US-20130023664-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NOS1, NOS2, NOS3 | CA12 4088/4885CA1 1871/4885CA2 2523/4885 |
| US-20140155616-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NOS1, NOS2, NOS3 | CA12 4088/4885CA1 1871/4885CA2 2523/4885 |
| US-20140194629-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NOS1, NOS2, NOS3 | CA12 4088/4885CA1 1871/4885CA2 2523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.