Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | CLTC | Q00610 | 10/20 | 0.64 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636204 | 0.85 | CLTC (0.72) | KDM4ECLTCNPSR1CA12CA1 | |
| SCHEMBL29226176 | 0.82 | KDM4E (1.00) | KDM4ECLTCNPSR1CA12CA1 | |
| SCHEMBL14636506 | 0.81 | CLTC (0.67) | KDM4ECLTCNPSR1CA12CA1 | |
| SCHEMBL14636119 | 0.78 | CA12 (0.78) | KDM4ECLTCRAD52NPSR1CA12 | |
| SCHEMBL14636024 | 0.78 | CLTC (0.79) | KDM4ECLTCNPSR1CA12CA1 | |
| SCHEMBL27169540 | 0.77 | NPSR1 (0.73) | KDM4ECLTCNPSR1CA12CA1 | |
| SCHEMBL29483205 | 0.77 | CLTC (0.98) | CLTCNPSR1CA12CA1CA2 | |
| SCHEMBL2365089 | 0.77 | MPO (0.58) | KDM4ECLTCNPSR1CA12CA1 | |
| SCHEMBL2365090 | 0.77 | MPO (0.58) | KDM4ECLTCNPSR1CA12CA1 | |
| SCHEMBL11435202 | 0.76 | HEXA (0.71) | KDM4ERAD52NPSR1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010218-A9 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013010218-A1 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-01-24 | — | — | WO | disclosed |