Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | CLTC | Q00610 | 10/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | STAT6 | P42226 | 1/20 | 0.55 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.55 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365089 | 1.00 | MPO (0.58) | MPOCLTCCYP2D6FTONPSR1 | |
| SCHEMBL27169540 | 0.88 | NPSR1 (0.73) | MPOCLTCCYP2D6FTONPSR1 | |
| SCHEMBL14636204 | 0.88 | CLTC (0.72) | MPOCLTCCYP2D6FTONPSR1 | |
| SCHEMBL2569297 | 0.82 | PABPC1 (0.60) | NPSR1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL2280844 | 0.81 | CA12 (0.71) | CLTCFTONPSR1MEN1POLB | |
| SCHEMBL2280848 | 0.81 | CA12 (0.71) | CLTCFTONPSR1MEN1POLB | |
| SCHEMBL14636506 | 0.77 | CLTC (0.67) | CLTCCYP2D6FTONPSR1KDM4E | |
| SCHEMBL2365312 | 0.77 | HEXA (0.74) | MPOCLTCCYP2D6FTONPSR1 | |
| SCHEMBL14635858 | 0.77 | KDM4E (0.69) | CLTCNPSR1MEN1POLBKMT2A | |
| SCHEMBL22717027 | 0.75 | MPO (0.62) | MPOCLTCCYP2D6FTONPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091209-A1 | SMALL MOLECULE MODIFIERS OF MICRORNA MIR-122 | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-07-28 | — | — | WO | disclosed |