Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12278299 | 0.84 | CYP3A4 (0.44) | ALOX5RAB9ANPC1TRPM8DCTPP1 | |
| SCHEMBL15999644 | 0.81 | ALOX5 (0.40) | ALOX5RAB9ANPC1TRPM8DCTPP1 | |
| SCHEMBL15999643 | 0.80 | CYP2A6 (0.53) | ALOX5RAB9ANPC1DCTPP1CYP19A1 | |
| SCHEMBL14654152 | 0.78 | CYP19A1 (0.45) | ALOX5RAB9ANPC1TRPM8CYP19A1 | |
| SCHEMBL12279509 | 0.77 | KDM4E (0.48) | RAB9ANPC1DCTPP1HTTCYP19A1 | |
| SCHEMBL12279301 | 0.77 | MEN1 (0.41) | ALOX5RAB9ANPC1TRPM8HTT | |
| SCHEMBL12278502 | 0.76 | HPGDS (0.50) | RAB9ANPC1DCTPP1HTTCYP3A4 | |
| SCHEMBL14654173 | 0.75 | TRPM8 (0.41) | ALOX5TRPM8CYP3A4CYP2C19MEN1 | |
| SCHEMBL14636146 | 0.74 | ALOX5 (0.44) | ALOX5RAB9ANPC1CYP19A1AXL | |
| SCHEMBL14635624 | 0.74 | ALOX5 (0.50) | ALOX5RAB9ANPC1HTTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140249024-A1 | Pesticidal Methods Using Substituted 3-pyridyl Thiazole Compounds and Derivatives for Combating Animal Pests II | BASF SE (DE) | 2014-09-04 | — | — | US | disclosed |
| US-20140249024-A1 | Pesticidal Methods Using Substituted 3-pyridyl Thiazole Compounds and Derivatives for Combating Animal Pests II | BASF SE (DE) | 2014-09-04 | — | — | US | disclosed |
| US-20140249024-A1 | Pesticidal Methods Using Substituted 3-pyridyl Thiazole Compounds and Derivatives for Combating Animal Pests II | BASF SE (DE) | 2014-09-04 | — | — | US | disclosed |
| EP-2731426-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS II | BASF SE (DE) | 2014-05-21 | — | — | EP | disclosed |
| WO-2013010947-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS II | BASF SE (DE) | 2013-01-24 | — | — | WO | disclosed |
| WO-2013010947-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS II | BASF SE (DE) | 2013-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249024-A1 | Pesticidal Methods Using Substituted 3-pyridyl Thiazole Compounds and Derivatives for Combating Animal Pests II | PTMS, PNPO, THOP1 | ALOX5 1099/4885RAB9A 2297/4885NPC1 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.