Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 6/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635686 | 0.90 | CLTC (0.76) | CLTCMEN1KMT2ABRD4USP2 | |
| SCHEMBL14636649 | 0.88 | CLTC (0.57) | CLTCMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL14636449 | 0.82 | CLTC (0.66) | CLTCMEN1KMT2AMAPK1USP2 | |
| SCHEMBL12559609 | 0.81 | CLTC (0.49) | CLTCMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL9352299 | 0.78 | ALDH1A1 (0.54) | CLTCMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL29365854 | 0.78 | ALDH1A1 (0.54) | CLTCMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL24270351 | 0.76 | HTT (0.64) | CLTCMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL9437193 | 0.75 | KMT2A (0.78) | MEN1KMT2AMAPK1L3MBTL1RAB9A | |
| SCHEMBL13428204 | 0.75 | CLTC (0.47) | CLTCMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL11769544 | 0.74 | TYMS (0.44) | CLTCMAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010218-A9 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013010218-A9 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013010218-A1 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-01-24 | — | — | WO | disclosed |
| WO-2013010218-A1 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-01-24 | — | — | WO | disclosed |