Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 2/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 4/20 | 0.39 |
| ▸ | HEXA | P06865 | 2/20 | 0.38 |
| ▸ | HEXB | P07686 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636147 | 0.88 | CLTC (0.63) | CLTCKEAP1NFE2L2TLR9MEN1 | |
| SCHEMBL14635686 | 0.85 | CLTC (0.76) | CLTCKEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL14636449 | 0.82 | CLTC (0.66) | CLTCMEN1KMT2AUSP2CYP1B1 | |
| SCHEMBL12559609 | 0.81 | CLTC (0.49) | CLTCKEAP1NFE2L2TLR9MEN1 | |
| SCHEMBL29365854 | 0.75 | ALDH1A1 (0.54) | CLTCKEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL9352299 | 0.75 | ALDH1A1 (0.54) | CLTCKEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL11769544 | 0.74 | TYMS (0.44) | CLTCALDH1A1MAPK1 | |
| SCHEMBL30608350 | 0.74 | TYMS (0.44) | CLTCALDH1A1MAPK1 | |
| SCHEMBL21404284 | 0.73 | CLTC (0.40) | CLTCMEN1KMT2ACYP2D6FTO | |
| SCHEMBL13428204 | 0.73 | CLTC (0.47) | CLTCKEAP1NFE2L2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010218-A9 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013010218-A1 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-01-24 | — | — | WO | disclosed |