Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 4/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | BRD1 | O95696 | 7/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 7/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006319 | 0.86 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL29365854 | 0.85 | ALDH1A1 (0.54) | CLTCALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL9352299 | 0.85 | ALDH1A1 (0.54) | CLTCALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL2474686 | 0.79 | KMT2A (0.68) | ALDH1A1LMNASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL29385571 | 0.79 | KMT2A (0.68) | ALDH1A1LMNASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL13656063 | 0.78 | CLTC (0.45) | CLTCALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL12203015 | 0.77 | SMN1; SMN2 (0.59) | ALDH1A1LMNASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL14635686 | 0.77 | CLTC (0.76) | CLTCALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL14636147 | 0.75 | CLTC (0.63) | CLTCALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL1502440 | 0.73 | CLTC (0.64) | CLTCALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8766238-B2 | Polymeric anions/cations | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-8766238-B2 | Polymeric anions/cations | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20100059740-A1 | POLYMERIC ANIONS/CATIONS | MERCK PATENT GMBH (DE) | 2010-03-11 | — | — | US | disclosed |