Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636285 | 0.77 | NPSR1 (0.44) | NPSR1L3MBTL1GAASLC6A4MAPT | |
| SCHEMBL27894789 | 0.70 | CAMK2A (0.70) | PPARGPPARDPPARACAMK2APTGDR2 | |
| SCHEMBL9995320 | 0.70 | SLC6A4 (0.52) | PPARAHTR2ASLC6A4KCNH2MAPT | |
| SCHEMBL27895144 | 0.69 | CAMK2A (0.56) | PPARGPPARDPPARATSPOCAMK2A | |
| SCHEMBL10093029 | 0.69 | L3MBTL1 (0.44) | NPSR1L3MBTL1GAAHTR2ASLC6A4 | |
| SCHEMBL5990380 | 0.69 | PPARG (0.64) | PPARGPPARDPPARAMEN1KMT2A | |
| SCHEMBL21723045 | 0.68 | CYP1A2 (0.53) | CAMK2ANPSR1L3MBTL1GAAHTR2A | |
| SCHEMBL1146416 | 0.66 | HTR2A (0.54) | PPARAPTGDR2HTR2ASLC6A4MAPT | |
| SCHEMBL5417843 | 0.66 | SLC6A4 (0.47) | NPSR1PTGDR2L3MBTL1HTR2ASLC6A4 | |
| SCHEMBL12929644 | 0.66 | CYP1A2 (0.57) | PPARGPPARDPPARAHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8779161-B2 | Asenapine maleate | DR. REDDY'S LABORATORIES LIMITED (IN) | 2014-07-15 | — | — | US | disclosed |
| US-20130211099-A1 | ASENAPINE MALEATE | DR. REDDY'S LABORATORIES, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| EP-2582704-A2 | ASENAPINE MALEATE | Dr. Reddy's Laboratories Ltd. (IN) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159903-A2 | ASENAPINE MALEATE | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130211099-A1 | ASENAPINE MALEATE | CYP3A5, AANAT, ADRA2C | PPARG 2193/4885PPARD 2105/4885PPARA 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.