Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064280 | 0.82 | RAB9A (0.49) | KMT2AMEN1CYP4F2CYP4A11THRB | |
| SCHEMBL7064350 | 0.78 | LMNA (0.55) | KMT2AMEN1KDM4EALDH1A1HSP90AA1 | |
| SCHEMBL3175977 | 0.74 | HTT (0.61) | KDM4EALDH1A1MAPTHTTCTBP2 | |
| SCHEMBL7899007 | 0.74 | MEN1 (0.55) | KMT2AMEN1KDM4EALDH1A1HSP90AA1 | |
| SCHEMBL7064540 | 0.72 | RAB9A (0.56) | KMT2AMEN1THRBALDH1A1HSP90AA1 | |
| SCHEMBL12704024 | 0.71 | HTT (0.53) | KMT2AMEN1GLAKDM4EALDH1A1 | |
| SCHEMBL28729704 | 0.70 | ALDH1A1 (0.47) | KMT2AMEN1THRBGLAKDM4E | |
| SCHEMBL6340092 | 0.69 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL2416902 | 0.69 | LIPE (0.54) | LIPEKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7641016 | 0.69 | HTT (0.54) | KMT2AMEN1GLAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013012118-A1 | NOVEL PHENYLESTER COMPOUND AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING THE SAME | SINIL PHARMACEUTICAL CO., LTD. (KR) | 2013-01-24 | — | — | WO | claimed |
| EP-2740458-B1 | Packaging comprising forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide | IP GES FÜR MAN MBH (DE) | 2016-08-03 | — | — | EP | disclosed |
| EP-2740458-A1 | Packaging comprising forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide | IP Gesellschaft für Management mbH (DE) | 2014-06-11 | — | — | EP | disclosed |
| WO-2013012118-A1 | NOVEL PHENYLESTER COMPOUND AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING THE SAME | SINIL PHARMACEUTICAL CO., LTD. (KR) | 2013-01-24 | — | — | WO | disclosed |
| WO-2013012118-A1 | NOVEL PHENYLESTER COMPOUND AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING THE SAME | SINIL PHARMACEUTICAL CO., LTD. (KR) | 2013-01-24 | — | — | WO | disclosed |