SCHEMBL7064280

SCHEMBL7064280

CCOC(=O)C(=O)Oc1ccc(CC)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.49
ALDH1A1 P00352 4/20 0.45
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
CYP2C19 P33261 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 4/20 0.43
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 2/20 0.43
HSP90AA1 P07900 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.41
THRB P10828 1/20 0.41
MAOB P27338 1/20 0.41
ELANE P08246 1/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064540 0.90 RAB9A (0.56) RAB9AALDH1A1RXRARXRBCYP2C19
SCHEMBL28729704 0.86 ALDH1A1 (0.47) RAB9AALDH1A1RXRARXRBCYP2C19
SCHEMBL7064350 0.85 LMNA (0.55) RAB9AALDH1A1CYP2C19SMN1; SMN2POLB
SCHEMBL1788228 0.83 RAB9A (0.50) RAB9AALDH1A1RXRARXRBCYP2C19
SCHEMBL7061682 0.83 RAB9A (0.54) RAB9AALDH1A1RXRARXRBCYP2C19
SCHEMBL14637553 0.82 LIPE (0.40) ALDH1A1KMT2AMAPTKDM4EMEN1
SCHEMBL9577400 0.81 RAB9A (0.51) RAB9AALDH1A1RXRARXRBCYP2C19
SCHEMBL7899007 0.81 MEN1 (0.55) RAB9AALDH1A1CYP2C19SMN1; SMN2KMT2A
SCHEMBL28956443 0.79 POLB (0.55) RAB9AALDH1A1RXRARXRBPOLB
SCHEMBL47952 0.78 RAB9A (0.56) RAB9AALDH1A1RXRARXRBCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1013633-B1 Process for producing a diaryl carbonate UBE INDUSTRIES (JP) 2003-05-28 EP disclosed
EP-0795539-B1 Process for producing a diaryl carbonate UBE INDUSTRIES (JP) 2001-10-31 EP disclosed
EP-0814074-B1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES (JP) 2001-03-28 EP disclosed
EP-1013633-A1 Process for producing a diaryl carbonate Ube Industries, Ltd. (JP) 2000-06-28 EP disclosed
US-6018072-A SUBJECTING AN ALKYLARYL OXALATE TO A DISPROPORTIONATION REACTION IN THE PRESENCE OF A DISPROPORTIONATION CATALYST TO PRODUCE A DIARYL OXALATE WHILE REMOVING A DIALKYL OXALATE BY-PRODUCT UBE INDUSTRIES, LTD. (JP) 2000-01-25 US disclosed
US-5811573-A Process for producing a diaryl carnonate UBE INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed
US-5731453-A Process for producing a diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed
EP-0814074-A1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES, LTD. (JP) 1997-12-29 EP disclosed
EP-0795539-A1 Process for producing a diaryl carbonate UBE INDUSTRIES LIMITED (JP) 1997-09-17 EP disclosed