Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.58 |
| ▸ | CTSS | P25774 | 6/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16084888 | 1.00 | CTSK (0.58) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL8279052 | 1.00 | CTSK (0.58) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL7280566 | 0.95 | CTSS (0.56) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL7273182 | 0.95 | CTSS (0.56) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL5551738 | 0.91 | CTSS (0.53) | CTSKCTSSITGB3ITGA2BLY96 | |
| SCHEMBL14051409 | 0.89 | ITGB3 (0.52) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL14632961 | 0.89 | CTSK (0.59) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL8271187 | 0.89 | CTSK (0.59) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL920111 | 0.88 | CTSS (0.63) | CTSKCTSSITGB3ITGA2BCTSL | |
| SCHEMBL7260689 | 0.88 | CTSS (0.63) | CTSKCTSSITGB3ITGA2BCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | CTSK 298/4885CTSS 277/4885ITGB3 3707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.